Hydrochloric Acid → N-(3-fluorophenyl)piperidin-4-amine

HRID 1235030Notes

Reaction equation

HRID 1235030 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][O:27][CH2:28]1.[ClH:22].[F:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 23137591tert-Butyl 4-(3-fluoroanilino)piperidine-1-carboxylate

Product 1

HCID 4778195N-(3-fluorophenyl)piperidin-4-amine

Sources & evidence

ORD record
ord-5e7ce503effc4e12b1985bb87e77644d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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