Ethanol → 3-Fluoro-4-(4-methylpiperazin-1-yl)aniline

HRID 1235329Notes

Reaction equation

HRID 1235329 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1.[CH3:36][CH2:37][OH:38].[F:25][c:26]1[cH:27][c:28]([N+:29]([O-:30])=[O:31])[cH:32][cH:33][c:34]1[F:35].[F:8][c:9]1[c:10]([N:18]2[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]2)[cH:11][cH:12][c:13]([N+:15]([O-:16])=[O:17])[cH:14]1>>[F:8][c:9]1[c:10]([N:18]2[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]2)[cH:11][cH:12][c:13]([NH2:15])[cH:14]1

Participants

5

Reactant 4

HCID 702EthanolHCID 531671-MethylpiperazineHCID 1230531,2-Difluoro-4-nitrobenzeneHCID 27830541-(2-Fluoro-4-nitrophenyl)-4-methylpiperazine

Product 1

HCID 27830553-Fluoro-4-(4-methylpiperazin-1-yl)aniline

Sources & evidence

ORD record
ord-508c01b506ed4c4987f7fb774a024cde
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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