Bromide ion → (+-)-1-(tert-Butoxycarbonyl)pyrrolidine-3-carboxaldehyde

HRID 1235508Notes

Reaction equation

HRID 1235508 reaction equation
[Br-:27].[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH:10]([CH2:13][OH:14])[CH2:11][CH2:12]1.[CH3:15][C:16]1([CH3:25])[N:17]([O:18])[C:19]([CH3:20])([CH3:21])[CH2:22][CH2:23][CH2:24]1.[Cl:28][O-:29].[Cl:36][CH2:37][Cl:38].[K+:26].[Na+:30].[Na+:35].[O-:31][C:32]([OH:33])=[O:34].[OH2:39]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH:10]([CH:13]=[O:14])[CH2:11][CH2:12]1

Participants

10

Reactant 9

HCID 259Bromide ionHCID 769Bicarbonate IonHCID 813Potassium CationHCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 61739HypochloriteHCID 5499762,2,6,6-Tetramethylpiperidin-1-olHCID 5237175tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 4692112(+-)-1-(tert-Butoxycarbonyl)pyrrolidine-3-carboxaldehyde

Sources & evidence

ORD record
ord-03a5f423149940deaf079c51e1ab443e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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