1,2-Dichloroethane → 4-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

HRID 1235782Notes

Reaction equation

HRID 1235782 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[c:16]([O:21][CH2:22][C:23](=[O:24])[OH:25])[cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH2:26]([Cl:27])[CH2:28][Cl:29].[OH:30][n:31]1[c:32]2[c:33]([cH:34][cH:35][cH:36][cH:37]2)[n:38][n:39]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[c:15]3[c:16]([cH:17][cH:18][cH:19][cH:20]3)[O:21][CH2:22][C:23]2=[O:24])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 111,2-DichloroethaneHCID 757711-HydroxybenzotriazoleHCID 223807041-t-Butyloxycarbonyl-4-((2-carboxymethoxyphenyl)amino)piperidine

Product 1

HCID 223806764-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-4a947cb2cd0444afa72878808f47c931
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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