Dichloromethane → Methyl 1-(4-(3-(cyclopropylmethyl)ureido)benzoyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperazine-2-carboxylate
Reaction equation
[CH2:52]([P:53]([OH:54])(=[O:55])[OH:56])[CH2:57][CH3:58].[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[CH:1]1([CH2:4][NH:5][C:6]([NH:7][c:8]2[cH:9][cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16]2)=[O:17])[CH2:2][CH2:3]1.[Cl:59][CH2:60][Cl:61].[F:18][C:19]([C:20]([C:21]([F:22])([F:23])[F:24])([OH:25])[c:26]1[cH:27][cH:28][c:29]([CH2:30][N:31]2[CH2:32][CH:33]([C:37](=[O:38])[O:39][CH3:40])[NH:34][CH2:35][CH2:36]2)[cH:41][cH:42]1)([F:43])[F:44]>>[CH:1]1([CH2:4][NH:5][C:6]([NH:7][c:8]2[cH:9][cH:10][c:11]([C:12](=[O:14])[N:34]3[CH:33]([C:37](=[O:38])[O:39][CH3:40])[CH2:32][N:31]([CH2:30][c:29]4[cH:28][cH:27][c:26]([C:20]([C:19]([F:18])([F:43])[F:44])([C:21]([F:22])([F:23])[F:24])[OH:25])[cH:42][cH:41]4)[CH2:36][CH2:35]3)[cH:15][cH:16]2)=[O:17])[CH2:2][CH2:3]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1a1b8f723efd4b3d97b2756287995069
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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