Tetrahydrofuran → HCID 178447066, compound

HRID 1235962Notes

Reaction equation

HRID 1235962 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][c:10]1[cH:11][c:12]([F:17])[cH:13][c:14]([F:16])[cH:15]1)[CH:18]1[O:19][CH2:20]1)=[O:21].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:22][C:23]1([CH3:40])[O:24][CH:25]2[CH:26]([N:27]1[C:28]([CH2:29][CH2:30][CH3:31])=[O:32])[c:33]1[cH:34][cH:35][cH:36][cH:37][c:38]1[CH2:39]2.[CH3:41][CH2:42][CH2:43][CH2:44][Li:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][c:10]1[cH:11][c:12]([F:17])[cH:13][c:14]([F:16])[cH:15]1)[CH:18]([OH:19])[CH2:20][CH:29]([C:28]([N:27]1[C:23]([CH3:22])([CH3:40])[O:24][CH:25]2[CH:26]1[c:33]1[cH:34][cH:35][cH:36][cH:37][c:38]1[CH2:39]2)=[O:32])[CH2:30][CH3:31])=[O:21]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 20726936Carbamic acid, [(1S)-2-(3,5-difluorophenyl)-1-(2R)-oxiranylethyl]-,1,1-dimethylethyl esterHCID 178418339ButyllithiumHCID 178454395HCID 178454395, compound

Product 1

HCID 178447066HCID 178447066, compound

Sources & evidence

ORD record
ord-b45a05e4995b495e836a02d8fac1711a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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