Dichloromethane → 1-(4-Ethoxy-2-fluorophenyl)piperazine

HRID 1235989Notes

Reaction equation

HRID 1235989 reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([F:19])[c:7]([N:10]2[CH2:11][CH2:12][N:13]([C:16]([OH:17])=[O:18])[CH2:14][CH2:15]2)[cH:8][cH:9]1.[Cl:20][CH2:21][Cl:22].[F:23][C:24]([F:25])([F:26])[C:27]([OH:28])=[O:29]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([F:19])[c:7]([N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 17968200HCID 17968200, compound

Product 1

HCID 179682601-(4-Ethoxy-2-fluorophenyl)piperazine

Sources & evidence

ORD record
ord-8cfbc446ec89453b8cba070e4a84a1a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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