Water → Ethyl 1-(6-amino-5-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)cyclobutanecarboxylate
Reaction equation
[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[CH3:43][O:44][CH2:45][CH2:46][O:47][CH3:48].[F:23][C:24]([c:25]1[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]1)([F:34])[F:35].[NH2:1][c:2]1[c:3]([Br:22])[cH:4][c:5]([C:13]2([C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH2:14][CH2:15][CH2:16]2)[cH:6][c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1.[OH2:42]>>[NH2:1][c:2]1[c:3](-[c:28]2[cH:27][cH:26][c:25]([C:24]([F:23])([F:34])[F:35])[cH:30][cH:29]2)[cH:4][c:5]([C:13]2([C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH2:14][CH2:15][CH2:16]2)[cH:6][c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-07f7a7e05cd04521951ef99505c5e3ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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