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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1236516Generated: November 3, 2026

Water → Tert-butyl 4-{2-[(3,5-bis-trifluoromethyl-benzyl)-(4'-fluoro-5'-isopropyl-4,5,2'-trimethoxy-biphenyl-2-ylmethyl)-amino]-pyrimidin-5-yloxy}-butyrate

https://huagongshe.com/reaction/1236516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acidHCID 53363739—
ReactantTert-butyl 4-{2-[(3,5-bis-trifluoromethyl-benzyl)-(2-bromo-4,5-dimethoxy-benzyl)-amino]-pyrimidin-5-yloxy}-butyrateHCID 86626904—
ProductTert-butyl 4-{2-[(3,5-bis-trifluoromethyl-benzyl)-(4'-fluoro-5'-isopropyl-4,5,2'-trimethoxy-biphenyl-2-ylmethyl)-amino]-pyrimidin-5-yloxy}-butyrateHCID 86626905—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-858313dab51749d9818c7a3f5cd3f43b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)