Chlorodifluoromethane → [3-(4-Bromobenzyl)-8-chloro-2-difluoromethoxy-4-methylquinolin-5-yloxy]acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][O:8][c:9]1[c:10]2[c:11]([CH3:29])[c:12]([CH2:21][c:22]3[cH:23][cH:24][c:25]([Br:28])[cH:26][cH:27]3)[c:13](=[O:20])[nH:14][c:15]2[c:16]([Cl:19])[cH:17][cH:18]1)=[O:30].[Cl:31][CH:32]([F:33])[F:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][O:8][c:9]1[c:10]2[c:11]([CH3:29])[c:12]([CH2:21][c:22]3[cH:23][cH:24][c:25]([Br:28])[cH:26][cH:27]3)[c:13]([O:20][CH:32]([F:33])[F:34])[n:14][c:15]2[c:16]([Cl:19])[cH:17][cH:18]1)=[O:30]Participants
3
Sources & evidence
- ORD record
- ord-2fdcedff676f48b794265def52901338
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…