Toluene → Methyl 2-{2-[(6-chloropyrimidin-4-yl)oxy]phenyl}-3-methoxyprop-2-enoate

HRID 1236912Notes

Reaction equation

HRID 1236912 reaction equation
[CH3:25][C:26]([O:27][C:28](=[O:29])[CH3:30])=[O:31].[CH3:32][S:33]([OH:34])(=[O:35])=[O:36].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[Cl:1][c:2]1[cH:3][c:4]([O:8][c:9]2[c:10]([CH:15]([C:16](=[O:17])[O:18][CH3:19])[CH:20]([O:21][CH3:22])[O:23][CH3:24])[cH:11][cH:12][cH:13][cH:14]2)[n:5][cH:6][n:7]1>>[Cl:1][c:2]1[cH:3][c:4]([O:8][c:9]2[c:10]([C:15]([C:16](=[O:17])[O:18][CH3:19])=[CH:20][O:21][CH3:22])[cH:11][cH:12][cH:13][cH:14]2)[n:5][cH:6][n:7]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6395Methanesulfonic AcidHCID 7918Acetic AnhydrideHCID 110136152-(2-(6-Chloro-pyrimidin-4-yloxy)-phenyl)-3,3-dimethoxy-propionic acid methyl ester

Product 1

HCID 53401286Methyl 2-{2-[(6-chloropyrimidin-4-yl)oxy]phenyl}-3-methoxyprop-2-enoate

Sources & evidence

ORD record
ord-4ed7f22acaca4668bcae2fb41d8bf19a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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