Methanol → 3-(3-(4-Cyclopropylmethoxy-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine
Reaction equation
[CH3:30][OH:31].[CH:23]1([CH2:26][Br:27])[CH2:24][CH2:25]1.[I-:29].[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]2)[n:11][o:12]1.[Na+:22].[Na+:28].[OH-:21]>>[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH2:26][CH:23]3[CH2:24][CH2:25]3)[cH:18][cH:19]2)[n:11][o:12]1Participants
7
Sources & evidence
- ORD record
- ord-d5a90b8910c7406ebf5d3faa2007f898
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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