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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1237163Generated: October 28, 2026

1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethan-1-ol → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/1237163

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethan-1-olHCID 58335252—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}thiophene-3-carboxamideHCID 59525803—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-23489f76c2c34b3ab90e28e5af4f26bd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)