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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1237675Generated: October 26, 2026

Methanol → 2-(5-Chloro-6-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-4,4,4-trifluorobutanoic acid

https://huagongshe.com/reaction/1237675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantEthyl 2-(5-chloro-6-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-4,4,4-trifluorobutanoateHCID 57995541—
Product2-(5-Chloro-6-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-4,4,4-trifluorobutanoic acidHCID 57995496—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-f58f73e0cb024c599ccf0cc69cc747c7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)