Methanol → 2-(5-Chloro-6-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-4,4,4-trifluorobutanoic acid
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:34][OH:35].[Cl:1][c:2]1[cH:3][c:4]([CH:23]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:29][C:30]([F:31])([F:32])[F:33])[cH:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1.[Li+:38].[OH-:37].[OH2:36].[OH2:39]>>[Cl:1][c:2]1[cH:3][c:4]([CH:23]([C:24](=[O:25])[OH:26])[CH2:29][C:30]([F:31])([F:32])[F:33])[cH:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f58f73e0cb024c599ccf0cc69cc747c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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