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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1237953Generated: October 28, 2026

Dimethylformamide → 1-(2,6-difluorophenyl)-7-[(2,4-difluorophenyl)ethynyl]-2H-quinolizin-2-one

https://huagongshe.com/reaction/1237953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-Ethynyl-2,4-difluorobenzeneHCID 5063820—
Reactant7-bromo-1-(2,6-difluorophenyl)-2H-quinolizin-2-oneHCID 57531230—
Product1-(2,6-difluorophenyl)-7-[(2,4-difluorophenyl)ethynyl]-2H-quinolizin-2-oneHCID 16749634—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-6e333cf5b743458cae324317bde8e2a1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)