Dichloromethane → Dimethyl 2-(3-fluorobenzyl)piperidine-1,4-dicarboxylate

HRID 1237962Notes

Reaction equation

HRID 1237962 reaction equation
[C:28]([O:29][CH3:30])(=[O:31])[Cl:32].[CH:19]([N:20]([CH2:21][CH3:22])[CH:23]([CH3:24])[CH3:25])([CH3:26])[CH3:27].[Cl:33][CH2:34][Cl:35].[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[NH:7][CH2:8][CH2:9][CH:10]([C:12](=[O:13])[O:14][CH3:15])[CH2:11]2)[cH:16][cH:17][cH:18]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[N:7]([C:28]([O:29][CH3:30])=[O:31])[CH2:8][CH2:9][CH:10]([C:12](=[O:13])[O:14][CH3:15])[CH2:11]2)[cH:16][cH:17][cH:18]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6586Methyl chloroformateHCID 81531DiisopropylethylamineHCID 66732105Methyl 2-(3-fluorobenzyl)piperidine-4-carboxylate

Product 1

HCID 66734612Dimethyl 2-(3-fluorobenzyl)piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-cebda39f07a84cb5aee38913468d42ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…