Methanol → 1-(difluoromethyl)-3-{4-[(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)oxy]phenyl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one
Reaction equation
[CH3:1][n:2]1[c:3]([S:11]([CH3:12])(=[O:13])=[O:14])[n:4][c:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2.[CH3:42][OH:43].[F:15][CH:16]([n:17]1[c:18](=[O:33])[n:19](-[c:26]2[cH:27][cH:28][c:29]([OH:32])[cH:30][cH:31]2)[c:20]2[n:21][cH:22][cH:23][cH:24][c:25]12)[F:34].[H-:36].[Na+:35].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[CH3:1][n:2]1[c:3]([O:32][c:29]2[cH:28][cH:27][c:26](-[n:19]3[c:18](=[O:33])[n:17]([CH:16]([F:15])[F:34])[c:25]4[c:20]3[n:21][cH:22][cH:23][cH:24]4)[cH:31][cH:30]2)[n:4][c:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9aa56135194f43778768066f77266107
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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