Potassium Cation → 3-chloro-N-[2-(dimethylamino)ethyl]-N-methyl-2-({4-[(1-methyl-1H-pyrazol-3-yl)amino]quinazolin-6-yl}oxy)isonicotinamide
Reaction equation
[CH3:18][C:19]([CH3:20])([O-:21])[CH3:22].[CH3:24][N:25]([CH3:26])[C:27](=[O:28])[CH3:29].[CH3:30][n:31]1[n:32][c:33]([NH:36][c:37]2[n:38][cH:39][n:40][c:41]3[cH:42][cH:43][c:44]([OH:47])[cH:45][c:46]23)[cH:34][cH:35]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([CH3:7])[CH2:8][CH2:9][N:10]([CH3:11])[CH3:12])[cH:13][cH:14][n:15][c:16]1[F:17].[K+:23].[OH2:48]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([CH3:7])[CH2:8][CH2:9][N:10]([CH3:11])[CH3:12])[cH:13][cH:14][n:15][c:16]1[O:47][c:44]1[cH:43][cH:42][c:41]2[n:40][cH:39][n:38][c:37]([NH:36][c:33]3[n:32][n:31]([CH3:30])[cH:35][cH:34]3)[c:46]2[cH:45]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-6eeb2e3104da435986189fb7e41570e6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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