Hydrochloric Acid → (1-{4-[8-(3-fluoro-azetidin-1-ylmethyl)-4-oxo-2-phenyl-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](-[c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[o:20][c:21]4[c:22]([CH:29]=[O:30])[cH:23][cH:24][cH:25][c:26]4[c:27]3=[O:28])[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:37].[C:44]([O:45][BH-:46]([O:47][C:48](=[O:49])[CH3:50])[O:51][C:52](=[O:53])[CH3:54])(=[O:55])[CH3:56].[Cl:58][CH:59]([Cl:60])[CH3:61].[ClH:38].[F:39][CH:40]1[CH2:41][NH:42][CH2:43]1.[Na+:57]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](-[c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[o:20][c:21]4[c:22]([CH2:29][N:42]5[CH2:41][CH:40]([F:39])[CH2:43]5)[cH:23][cH:24][cH:25][c:26]4[c:27]3=[O:28])[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:37]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e92dc3bced0446499b5c0a0a7d2c82a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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