Hydrochloric Acid → 4-(6-Fluoro-7-morpholin-4-yl-quinazolin-4-yl)-piperidine-1-carboxylic acid (4-pyrrolidin-1-yl-phenyl)-amide
Reaction equation
[C:1]([O:2][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([N:25]4[CH2:26][CH2:27][O:28][CH2:29][CH2:30]4)[c:21]([F:24])[cH:22][c:23]23)[CH2:12][CH2:13]1)([CH3:3])([CH3:4])[CH3:5].[ClH:31].[N+:32]([c:33]1[cH:34][cH:35][c:36]([O:37][C:38](=[O:39])[NH:43][c:44]2[cH:45][cH:46][c:47]([N:50]3[CH2:51][CH2:52][CH2:53][CH2:54]3)[cH:48][cH:49]2)[cH:40][cH:41]1)([O-:42])=[O:55]>>[C:6](=[O:7])([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([N:25]4[CH2:26][CH2:27][O:28][CH2:29][CH2:30]4)[c:21]([F:24])[cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:43][c:44]1[cH:45][cH:46][c:47]([N:50]2[CH2:51][CH2:52][CH2:53][CH2:54]2)[cH:48][cH:49]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a1f0473ef2384ac18ae7ca980311bd8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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