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HRID12385

反应详情

EQUATION

反应方程式

HRID 12385 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：O=C1Cc2ccccc2N1
HCID321710

1,3-Dihydro-2H-indol-2-one

C8H7NO

PRODUCTS

生成物

1
结构：CC(=O)N1C(=O)Cc2ccccc21
HCID323719

1-acetylindolin-2-one

C10H9NO2

收率 93.7%

PROCEDURE

实验过程

Indoline-2-one (6.65 g, 50 mmol) and acetic anhydride (9 mL) were heated at reflux for 15 h. After cooling, the product was filtered and rinsed with Et2O to give 2a as solids after vacuum drying (8.2 g, yield: 93.7 %).

WORKUP

后处理

  1. temperatureat reflux for 15 h
  2. temperatureAfter cooling
  3. filtrationthe product was filtered
  4. washrinsed with Et2O