Hydrochloric Acid → 2-Bromo-5-[2-(4-cyclobutylpiperazin-1-yl)-2-oxoethyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine
Reaction equation
[Br:2][c:3]1[s:4][c:5]2[c:10]([n:11]1)[CH2:9][CH2:8][NH:7][CH2:6]2.[CH3:32][C:33]#[N:34].[Cl:12][CH2:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][N:19]([CH:22]2[CH2:23][CH2:24][CH2:25]2)[CH2:20][CH2:21]1.[ClH:1].[K+:26].[K+:27].[O-:28][C:29]([O-:30])=[O:31]>>[Br:2][c:3]1[s:4][c:5]2[c:10]([n:11]1)[CH2:9][CH2:8][N:7]([CH2:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][N:19]([CH:22]3[CH2:23][CH2:24][CH2:25]3)[CH2:20][CH2:21]1)[CH2:6]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-78ad8780cd3a4dacab1eba389545f78a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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