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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238764Generated: November 1, 2026

Chloride → 3-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl)phenoxy]-3,4-dihydro-1H-pyridin-2-one

https://huagongshe.com/reaction/1238764

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
ReactantLithium ionHCID 28486—
Reactant3-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl)phenoxy]-3-methoxycarbonyl-3,4-dihydro-1H-pyridin-2-oneHCID 12097348—
Product3-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl)phenoxy]-3,4-dihydro-1H-pyridin-2-oneHCID 12097349—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-7e3dc5a24dbb4c438857dd3cbf92c689
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)