Chloride → 3-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl)phenoxy]-3,4-dihydro-1H-pyridin-2-one
Reaction equation
[CH3:36][S:37](=[O:38])[CH3:39].[Cl-:35].[Cl:1][c:2]1[c:3]([O:4][C:5]2([C:12]([O:13][CH3:14])=[O:15])[C:6](=[O:11])[NH:7][CH:8]=[CH:9][CH2:10]2)[cH:16][c:17](-[n:21]2[c:22](=[O:33])[n:23]([CH3:32])[c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]2=[O:27])[c:18]([F:20])[cH:19]1.[Li+:34].[OH2:40]>>[Cl:1][c:2]1[c:3]([O:4][CH:5]2[C:6](=[O:11])[NH:7][CH:8]=[CH:9][CH2:10]2)[cH:16][c:17](-[n:21]2[c:22](=[O:33])[n:23]([CH3:32])[c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]2=[O:27])[c:18]([F:20])[cH:19]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7e3dc5a24dbb4c438857dd3cbf92c689
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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