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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238832Generated: November 1, 2026

Tetrahydrofuran → 3-(4,5-dichloropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

https://huagongshe.com/reaction/1238832

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanoneHCID 588080—
ReactantDiisopropylamideHCID 5062348—
Reactant4,5-Dichloro-6-ethylpyrimidineHCID 11137668—
Product3-(4,5-dichloropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-olHCID 15230633—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-8ccfb037add949d78b26972c7f1883ea
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)