Tetrahydrofuran → 3-(4,5-dichloropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:2][CH:3]([N-:4][CH:5]([CH3:6])[CH3:7])[CH3:8].[Cl:9][c:10]1[n:11][cH:12][n:13][c:14]([CH2:17][CH3:18])[c:15]1[Cl:16].[F:19][c:20]1[c:21]([C:27]([CH2:28][n:29]2[n:30][cH:31][n:32][cH:33]2)=[O:34])[cH:22][cH:23][c:24]([F:26])[cH:25]1.[Li+:1]>>[Cl:9][c:10]1[n:11][cH:12][n:13][c:14]([CH:17]([CH3:18])[C:27]([c:21]2[c:20]([F:19])[cH:25][c:24]([F:26])[cH:23][cH:22]2)([CH2:28][n:29]2[n:30][cH:31][n:32][cH:33]2)[OH:34])[c:15]1[Cl:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8ccfb037add949d78b26972c7f1883ea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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