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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 123885Generated: October 30, 2026

1,4-Dioxane → [8-(3,5-Bis-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-fluoro-1-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-yl]-amine

https://huagongshe.com/reaction/123885

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Bromo-5-methyl-1,3,4-oxadiazoleHCID 25219536—
Reactant8-(3,5-bis(trifluoromethyl)phenyl)-N-(3-fluoropiperidin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amineHCID 86656725—
Product[8-(3,5-Bis-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-fluoro-1-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-yl]-amineHCID 76775944—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-7a46606a258444b9819334570e68b30c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)