1,4-Dioxane → [8-(3,5-Bis-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-fluoro-1-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-yl]-amine
Reaction equation
[Br:32][c:33]1[o:34][c:35]([CH3:38])[n:36][n:37]1.[CH:39]([N:40]([CH:41]([CH3:42])[CH3:43])[CH2:44][CH3:45])([CH3:46])[CH3:47].[F:1][C:2]([c:3]1[cH:4][c:5](-[c:13]2[c:14]3[n:15]([cH:16][cH:17][cH:18]2)[n:19][c:20]([NH:22][CH:23]2[CH:24]([F:29])[CH2:25][NH:26][CH2:27][CH2:28]2)[n:21]3)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:30])[F:31].[O:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:13]2[c:14]3[n:15]([cH:16][cH:17][cH:18]2)[n:19][c:20]([NH:22][CH:23]2[CH:24]([F:29])[CH2:25][N:26]([c:33]4[o:34][c:35]([CH3:38])[n:36][n:37]4)[CH2:27][CH2:28]2)[n:21]3)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:30])[F:31]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-7a46606a258444b9819334570e68b30c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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