Tetrahydrofuran → Methyl 2-(pyridin-2-yl)thiazole-5-carboxylate
Reaction equation
[Br:11][Zn:12][c:13]1[n:14][cH:15][cH:16][cH:17][cH:18]1.[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][n:7][c:8]([Br:10])[s:9]1.[cH:24]1[cH:25][cH:26][c:27]([P:28]([Pd:29]([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[cH:99][cH:100]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][n:7][c:8](-[c:13]2[n:14][cH:15][cH:16][cH:17][cH:18]2)[s:9]1Participants
5
Sources & evidence
- ORD record
- ord-1440ce90ce1a46dba40d7b71d1f44156
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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