Dichloromethane → [4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-5-trifluoromethyl-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-chloromethyl-phenyl)-methanone

HRID 1239058Notes

Reaction equation

HRID 1239058 reaction equation
[CH2:51]([Cl:52])[Cl:53].[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[Cl:19][c:20]1[cH:21][cH:22][c:23]([CH:26]2[N:27]=[C:28]([c:38]3[c:39]([O:48][CH2:49][CH3:50])[cH:40][cH:41][c:42]([C:44]([F:45])([F:46])[F:47])[cH:43]3)[NH:29][CH:30]2[c:31]2[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]2)[cH:24][cH:25]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[Cl:9])[cH:10][cH:11]1>>[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[N:29]2[C:28]([c:38]3[c:39]([O:48][CH2:49][CH3:50])[cH:40][cH:41][c:42]([C:44]([F:45])([F:46])[F:47])[cH:43]3)=[N:27][CH:26]([c:23]3[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]3)[CH:30]2[c:31]2[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]2)[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 701364-(Chloromethyl)benzoyl chlorideHCID 597926464,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-5-trifluoromethyl-phenyl)-4,5-dihydro-1H-imidazole

Product 1

HCID 86595531[4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-5-trifluoromethyl-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-chloromethyl-phenyl)-methanone

Sources & evidence

ORD record
ord-1e0010871dc74d04a8100625ef29d202
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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