Hydrochloric Acid → 8-Methyl-3-(piperazin-1-yl)-8-azabicyclo[3.2.1]octane

HRID 1239144Notes

Reaction equation

HRID 1239144 reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][N:12]([CH:15]2[CH2:16][CH:17]3[CH2:18][CH2:19][CH:20]([CH2:21]2)[N:22]3[CH3:23])[CH2:13][CH2:14]1.[CH3:24][OH:25].[ClH:1].[ClH:26].[Na+:28].[OH-:27].[OH-:29].[OH-:31].[Pd+2:30]>>[NH:9]1[CH2:10][CH2:11][N:12]([CH:15]2[CH2:16][CH:17]3[CH2:18][CH2:19][CH:20]([CH2:21]2)[N:22]3[CH3:23])[CH2:13][CH2:14]1

Participants

7

Reactant 6

HCID 313Hydrochloric Acid2×HCID 887MethanolHCID 923Sodium ionHCID 961Hydroxide3×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 28463331-benzyl-4-(N-methyl-8-azabicyclo[3,2,1]oct-3-yl)-piperazine

Product 1

HCID 154797638-Methyl-3-(piperazin-1-yl)-8-azabicyclo[3.2.1]octane

Sources & evidence

ORD record
ord-157a9fa74e45417782db491f0f9c02af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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