Dimethyl Sulfoxide → 2-{3-[(2,2-Difluoro-2-phenylethyl)amino]-6-chloro-2-fluorophenyl}ethanal
Reaction equation
[CH3:1][S:2]([CH3:3])=[O:4].[CH:5]([N:6]([CH2:7][CH3:8])[CH:9]([CH3:10])[CH3:11])([CH3:12])[CH3:13].[Cl:46][CH2:47][Cl:48].[F:14][C:15]([CH2:16][NH:17][c:18]1[c:19]([F:28])[c:20]([CH2:25][CH2:26][OH:27])[c:21]([Cl:24])[cH:22][cH:23]1)([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[F:35].[S:42](=[O:43])(=[O:44])=[O:45].[n:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[F:14][C:15]([CH2:16][NH:17][c:18]1[c:19]([F:28])[c:20]([CH2:25][CH:26]=[O:27])[c:21]([Cl:24])[cH:22][cH:23]1)([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[F:35]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-061970b9cfad4fba839d3d24c4896db1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…