Potassium Cation → Benzyl 4-(2-oxo-1,3-diazinan-1-yl)piperidine-1-carboxylate

HRID 1239232Notes

Reaction equation

HRID 1239232 reaction equation
[Br:34][CH2:35][C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([N:17]2[C:18](=[O:27])[N:19]([CH2:23][C:24]([OH:25])=[O:26])[CH2:20][CH2:21][CH2:22]2)[CH2:15][CH2:16]1.[CH2:52]([N+:53]([CH2:54][CH2:55][CH2:56][CH3:57])([CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH2:64][CH3:65])[CH2:66][CH2:67][CH3:68].[CH3:28][C:29]([CH3:30])([O-:31])[CH3:32].[Cl:48][CH2:49][Cl:50].[I-:51].[K+:33].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([N:17]2[C:18](=[O:27])[NH:19][CH2:20][CH2:21][CH2:22]2)[CH2:15][CH2:16]1

Participants

9

Reactant 8

HCID 813Potassium CationHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 30165Iodide IonHCID 79177tert-Butyl bromoacetateHCID 45749132-Methylpropan-2-olateHCID 22137504[3-{1-[(Benzyloxy)carbonyl]piperidin-4-yl}-2-oxotetrahydropyrimidin-1(2H)-yl]acetic acid

Product 1

HCID 22137530Benzyl 4-(2-oxo-1,3-diazinan-1-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-8b26d3e18ad341eb8d0f30312e62ef5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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