Dichloromethane → 2-Methoxyethyl 4-[2-[[5-[2-[2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate

HRID 1239553Notes

Reaction equation

HRID 1239553 reaction equation
[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[CH3:47][O:48][CH2:49][CH2:50][O:51][C:52](=[O:53])[Cl:54].[Cl:55][CH2:56][Cl:57].[O:1]=[C:2]([CH2:3][NH:4][C:5](=[O:6])[c:7]1[n:8][n:9](-[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:10]([O:12][CH2:13][C:14](=[O:15])[N:16]2[CH:17]([C:21]([NH:22][CH:23]3[CH2:24][CH2:25][CH2:26]3)=[O:27])[CH2:18][CH2:19][CH2:20]2)[cH:11]1)[N:34]1[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1>>[O:1]=[C:2]([CH2:3][NH:4][C:5](=[O:6])[c:7]1[n:8][n:9](-[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:10]([O:12][CH2:13][C:14](=[O:15])[N:16]2[CH:17]([C:21]([NH:22][CH:23]3[CH2:24][CH2:25][CH2:26]3)=[O:27])[CH2:18][CH2:19][CH2:20]2)[cH:11]1)[N:34]1[CH2:35][CH2:36][N:37]([C:52]([O:51][CH2:50][CH2:49][O:48][CH3:47])=[O:53])[CH2:38][CH2:39]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 694002-Methoxyethyl chloroformateHCID 178523534HCID 178523534, compound

Product 1

HCID 668555602-Methoxyethyl 4-[2-[[5-[2-[2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-b0ee1fea5fe248ef9f84776218c918a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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