Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1239751Generated: October 29, 2026

Phosphorus oxychloride → Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate

https://huagongshe.com/reaction/1239751

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantEthyl 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-methoxy-4-oxo-1,8-naphthyridine-3-carboxylateHCID 13849333—
ProductEthyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylateHCID 1268243—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-2ca8dddc0a2c48aa910a48e477e60eb5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)