Tetrahydrofuran → 3-cyclopentyl-3-[4-(5-iodo-2-methoxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Reaction equation
[CH:1]1([CH:6]([CH2:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][c:19]([O:21][CH3:22])[n:20]3)[nH:23][cH:24][cH:25]4)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[I:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[CH:1]1([CH:6]([CH2:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][c:19]([O:21][CH3:22])[n:20]3)[nH:23][cH:24][c:25]4[I:26])[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
4
Sources & evidence
- ORD record
- ord-aad2100793014dd3b90580e2d8dabf68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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