Hydrochloric Acid → N-[[3-cyano-5-fluoro-4-(methanesulfonamido)phenyl]methyl]-3-[2-morpholin-4-yl-6-(trifluoromethyl)pyridin-3-yl]prop-2-enamide
Reaction equation
[CH3:18][N:19]([CH3:20])[c:21]1[c:22]([CH:23]=[CH:24][C:25]([OH:26])=[O:27])[cH:28][cH:29][c:30]([C:31]([F:32])([F:33])[F:34])[n:35]1.[ClH:17].[NH2:1][CH2:2][c:3]1[cH:4][c:5]([F:16])[c:6]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[c:7]([C:9]#[N:10])[cH:8]1.[O:36]1[CH2:37][CH2:38][N:39]([c:42]2[n:43][c:44]([C:53]([F:54])([F:55])[F:56])[cH:45][cH:46][c:47]2[CH:48]=[CH:49][C:50](=[O:51])[OH:52])[CH2:40][CH2:41]1>>[NH:1]([CH2:2][c:3]1[cH:4][c:5]([F:16])[c:6]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[c:7]([C:9]#[N:10])[cH:8]1)[C:50]([CH:49]=[CH:48][c:47]1[c:42]([N:39]2[CH2:38][CH2:37][O:36][CH2:41][CH2:40]2)[n:43][c:44]([C:53]([F:54])([F:55])[F:56])[cH:45][cH:46]1)=[O:51]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8111b87a810440daabf1ec904503a2d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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