1,3-Dibromo-5,5-dimethylhydantoin → N-[3-(5-bromo-4-hydroxy-1-isopentyl-2-oxo-1,2-dihydro-3-pyridinyl)-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl]methanesulfonamide

HRID 124004Notes

Reaction equation

HRID 124004 reaction equation
[Br:31][N:32]1[C:33]([CH3:34])([CH3:35])[C:36](=[O:37])[N:38]([Br:39])[C:40]1=[O:41].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1.[OH:1][c:2]1[c:3]([C:14]2=[N:15][S:16](=[O:29])(=[O:30])[c:17]3[c:18]([cH:20][cH:21][c:22]([NH:24][S:25](=[O:26])(=[O:27])[CH3:28])[cH:23]3)[NH:19]2)[c:4](=[O:13])[n:5]([CH2:8][CH2:9][CH:10]([CH3:11])[CH3:12])[cH:6][cH:7]1>>[OH:1][c:2]1[c:3]([C:14]2=[N:15][S:16](=[O:29])(=[O:30])[c:17]3[c:18]([cH:20][cH:21][c:22]([NH:24][S:25](=[O:26])(=[O:27])[CH3:28])[cH:23]3)[NH:19]2)[c:4](=[O:13])[n:5]([CH2:8][CH2:9][CH:10]([CH3:11])[CH3:12])[cH:6][c:7]1[Br:31]

Participants

4

Reactant 3

HCID 64791,3-Dibromo-5,5-dimethylhydantoinHCID 8028TetrahydrofuranHCID 136036674N-[3-(4-hydroxy-1-isopentyl-2-oxo-3-pyridyl)-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazin-7-yl]methanesulfonamide

Product 1

HCID 136036672N-[3-(5-bromo-4-hydroxy-1-isopentyl-2-oxo-1,2-dihydro-3-pyridinyl)-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl]methanesulfonamide

Sources & evidence

ORD record
ord-f74baf1b2add48309dd9c59441b04ea7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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