1-Methylimidazole → tert-butyl 4-hydroxy-4-(1-methyl-1H-imidazol-2-yl)piperidine-1-carboxylate
Reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:1][n:2]1[cH:3][cH:4][n:5][cH:6]1.[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36].[O:12]=[C:13]1[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]1>>[CH3:1][n:2]1[cH:3][cH:4][n:5][c:6]1[C:13]1([OH:12])[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]1Participants
6
Sources & evidence
- ORD record
- ord-ab65a3c9bfb74f67b66eeaeda03b9775
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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