4-Bromoanisole → 3-(4-methoxyphenyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH3:15][N:16]1[CH:17]2[CH2:18][C:19](=[O:24])[CH2:20][CH:21]1[CH2:22][CH2:23]2.[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:2]1([C:19]2([OH:24])[CH2:18][CH:17]3[N:16]([CH3:15])[CH:21]([CH2:20]2)[CH2:22][CH2:23]3)[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-03d0a6b18d664e2483c5d33028da0127
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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