Methanol → 2-[4-(Aminomethyl)cyclohexyl]propan-2-ol

HRID 1240524Notes

Reaction equation

HRID 1240524 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:10][CH2:11][CH:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:22]1.[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[CH3:32][OH:33].[OH-:29].[OH-:30].[Pd+2:31]>>[NH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 20583515trans-[4-(1-Hydroxy-1-methyl-ethyl)-cyclohexylmethyl]-carbamic acid benzyl ester

Product 1

HCID 187349312-[4-(Aminomethyl)cyclohexyl]propan-2-ol

Sources & evidence

ORD record
ord-65ca666ff1e6449080cb6146796b018a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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