HRID1240545

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7912

Diisopropylamine

C6H15N

HCID8028

Tetrahydrofuran

C4H8O

HCID77877

(Iodomethyl)trimethylsilane

C4H11ISi

HCID10786069

Pyridine,2-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]-

C17H14F3N3O2S

HCID178418339

Butyllithium

C4H9Li

PRODUCTS

产物

HCID22997772

2-methyl-3-[1-[4-[[2-(trimethylsilyl)ethyl]sulfonyl]phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine

C21H24F3N3O2SSi

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-be3cb46bc42e4316ae9ccdd60d388fbe
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (5/10)

反应SMILES

[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:13][c:14]1[n:15][cH:16][cH:17][cH:18][c:19]1-[c:20]1[n:21](-[c:29]2[cH:30][cH:31][c:32]([S:35](=[O:36])(=[O:37])[CH3:38])[cH:33][cH:34]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]1.[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[I:39][CH2:40][Si:41]([CH3:42])([CH3:43])[CH3:44].[Li:8][CH2:9][CH2:10][CH2:11][CH3:12]>>[CH3:13][c:14]1[n:15][cH:16][cH:17][cH:18][c:19]1-[c:20]1[n:21](-[c:29]2[cH:30][cH:31][c:32]([S:35](=[O:36])(=[O:37])[CH2:38][CH2:40][Si:41]([CH3:42])([CH3:43])[CH3:44])[cH:33][cH:34]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]1