Bromide ion → 2-[6-(-Benzyloxy-but-1-enyl)-benzoimidazol-1-yl]-4-(3-chloro-phenyl)-thiazole-5-carboxylic acid ethyl ester
Reaction equation
[Br-:1].[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][CH2:10][CH2:11][CH2:12][P+:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[CH2:39]([CH3:40])[O:41][C:42](=[O:43])[c:44]1[c:45](-[c:60]2[cH:61][c:62]([Cl:66])[cH:63][cH:64][cH:65]2)[n:46][c:47](-[n:49]2[cH:50][n:51][c:52]3[c:53]2[cH:54][c:55]([CH:58]=[O:59])[cH:56][cH:57]3)[s:48]1.[Li:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[O:67]1[CH2:68][CH2:69][CH2:70][CH2:71]1>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][CH2:10][CH2:11][CH:12]=[CH:58][c:55]1[cH:54][c:53]2[n:49](-[c:47]3[n:46][c:45](-[c:60]4[cH:61][c:62]([Cl:66])[cH:63][cH:64][cH:65]4)[c:44]([C:42]([O:41][CH2:39][CH3:40])=[O:43])[s:48]3)[cH:50][n:51][c:52]2[cH:57][cH:56]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4a18ca90256c4c398567f1189423f220
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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