Potassium Cation → 2,6-Difluoro-3-[2-(4-methoxy-phenyl)-oxazol-4-ylmethoxy]-benzamide

HRID 1240592Notes

Reaction equation

HRID 1240592 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[Cl:1][CH2:2][c:3]1[n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]2)[o:6][cH:7]1.[F:16][c:17]1[c:18]([C:19](=[O:20])[NH2:21])[c:22]([F:27])[cH:23][cH:24][c:25]1[OH:26].[K+:32].[K+:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[CH2:2]([c:3]1[n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]2)[o:6][cH:7]1)[O:26][c:25]1[c:17]([F:16])[c:18]([C:19](=[O:20])[NH2:21])[c:22]([F:27])[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 199587944-(Chloromethyl)-2-(4-methoxyphenyl)-1,3-oxazoleHCID 451201362,6-Difluoro-3-hydroxybenzamide

Product 1

HCID 594029482,6-Difluoro-3-[2-(4-methoxy-phenyl)-oxazol-4-ylmethoxy]-benzamide

Sources & evidence

ORD record
ord-a1abece4cecc4665a5fdf08e2df230b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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