Hexane → 4-(3-Chlorophenoxy)-6-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-[1,8]naphthyridine

HRID 1240800Notes

Reaction equation

HRID 1240800 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:9]([n:10][cH:11]1)[NH:8][CH2:7][CH2:6][CH:5]2[O:12][c:13]1[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]1.[C:47]([O:48][CH2:49][CH3:50])(=[O:51])[CH3:52].[CH3:20][C:21]1([CH3:22])[C:23]([CH3:24])([CH3:25])[O:26][B:27]([c:28]2[cH:29][c:30]([N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)[cH:31][cH:32][cH:33]2)[O:40]1.[CH3:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]>>[c:2]1(-[c:28]2[cH:29][c:30]([N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)[cH:31][cH:32][cH:33]2)[cH:3][c:4]2[c:9]([n:10][cH:11]1)[NH:8][CH2:7][CH2:6][CH:5]2[O:12][c:13]1[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]1

Participants

5

Reactant 4

HCID 8058HexaneHCID 8857Ethyl AcetateHCID 41926634-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholineHCID 578858956-Bromo-4-(3-chlorophenoxy)-1,2,3,4-tetrahydro-[1,8]naphthyridine

Product 1

HCID 578859534-(3-Chlorophenoxy)-6-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-[1,8]naphthyridine

Sources & evidence

ORD record
ord-4508e7fc83e14d4fb6c80d54ccd7f800
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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