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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1240871Generated: October 31, 2026

Methanol → 4-[4-(2-fluoroethyl)-3-(2-methoxyethyl)piperazin-1-yl]-2-(trifluoromethyl)-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepine

https://huagongshe.com/reaction/1240871

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantWaterHCID 962—
ReactantEthylenediamineHCID 3301—
ReactantBoraneHCID 6331—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
Reactant2-fluoro-1-[2-(2-methoxyethyl)-4-[2-(trifluoromethyl)-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepin-4-yl]piperazin-1-yl]ethanoneHCID 136394875—
Product4-[4-(2-fluoroethyl)-3-(2-methoxyethyl)piperazin-1-yl]-2-(trifluoromethyl)-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepineHCID 136384200—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-1093b208cdda4e029e61cb97f59c961e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)