Dichloromethane → 2-cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (4-hydroxymethyl-tetrahydro-pyran-4-yl)-amide
Reaction equation
[Cl:39][CH2:40][Cl:41].[OH:1][CH2:2][C:3]1([NH:9][C:10](=[O:11])[c:12]2[cH:13][n:14]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[c:15]3[n:16][cH:17][c:18]([CH:21]4[CH2:22][CH2:23]4)[n:19][c:20]23)[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1.[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[OH:1][CH2:2][C:3]1([NH:9][C:10](=[O:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18]([CH:21]4[CH2:22][CH2:23]4)[n:19][c:20]23)[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2f83f98012f64fdeb49c621f5e26b57c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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