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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1241389Generated: October 30, 2026

6-Chloro-2-methylpyrimidin-4-amine → HCID 21934648, compound

https://huagongshe.com/reaction/1241389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-methylpyrimidin-4-amineHCID 286754—
Reactant4-(2-Piperazin-1-yl-ethyl)-morpholineHCID 2734640—
ProductHCID 21934648HCID 21934648—

Reaction Steps

210 mg (1.47 mmol) of 2-methyl-4-chloro-6-aminopyrimidine 20-1 and 294 mg (1.47 mmol) of 4-(2-piperazin-1-ylethyl)morpholine 7-3 were used to obtain the desired product 20-2 as a yellow oil/solid. MS M+1=307. H1 NMR (CDCl3): 2.37(s, 3H), 2.53(br m, 4H), 2.57(br m, 4H), 3.57(m, 4H), 3.73(m, 4H), 4.52(br s, 2H), 5.41(s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115597B2
Source datasetuspto-grants-2006_10
ORD IDord-887af24374724aa1b81d9a5863d0b9c7
Source noteuspto-grants-2006_10