HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 178473905, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 178427759 | HCID 178427759 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 178473905 | HCID 178473905 | — |
Reaction Steps
Preparation as described for Example 100, General Procedure A, Step H, using the appropriated amine and the tosylate of Example 47 (cis-toluene-4-sulfonic acid 3-(4-pyrrolidin-1-ylmethyl-phenyl)-cyclobutylmethyl ester). Rf=0.24 (20% MeOH/CH2Cl2 w/0.5% NH4OH); LRMS m/z Calcd for C22H33N3O 355.5; obsd LRMS APCI (M+1) m/z 356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115600B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-ec1b987ccf364584a0d6f4584cfec659 |
| Source note | uspto-grants-2006_10 |